TB-Profiler result

Run: ERR9882544
Summary

Run ID: ERR9882544

Sample name:

Date: 02-04-2023 13:24:35

Number of reads: 704328

Percentage reads mapped: 99.48

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
fgd1 491423 p.Gly214Val missense_variant 0.12
mshA 576538 p.Gln397His missense_variant 0.11
rpoB 761599 p.Arg598His missense_variant 0.18
rpoB 763104 c.3299delT frameshift_variant 0.11
rpoB 763134 p.Gly1110Cys missense_variant 0.12
rpoC 766254 c.2886delG frameshift_variant 0.12
mmpL5 775666 c.2814delG frameshift_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673346 c.-94C>G upstream_gene_variant 0.13
fabG1 1673349 c.-91G>C upstream_gene_variant 0.13
fabG1 1673357 c.-83G>A upstream_gene_variant 0.11
fabG1 1673359 c.-81T>C upstream_gene_variant 0.11
fabG1 1673361 c.-79C>G upstream_gene_variant 0.12
fabG1 1673380 c.-60C>G upstream_gene_variant 0.17
PPE35 2170048 p.Leu189Val missense_variant 0.15
PPE35 2170053 p.Thr187Ser missense_variant 0.1
kasA 2519184 p.Leu357Pro missense_variant 0.11
fbiD 3339200 p.Pro28Leu missense_variant 0.11
clpC1 4038727 p.Thr660Ala missense_variant 0.11
clpC1 4038806 p.Glu633Asp missense_variant 0.12