TB-Profiler result

Run: ERR9882557

Summary

Run ID: ERR9882557

Sample name:

Date: 02-04-2023 13:26:13

Number of reads: 739559

Percentage reads mapped: 99.42

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 765578 c.2209C>T synonymous_variant 0.11
rpoC 766891 c.3527delT frameshift_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.24
katG 2154831 c.1281T>C synonymous_variant 0.11
PPE35 2169910 p.Asn235Asp missense_variant 0.1
pepQ 2859624 c.795G>T synonymous_variant 0.11
fprA 3474944 p.Leu313Pro missense_variant 0.11
embC 4243032 p.Trp1057Leu missense_variant 0.11
embA 4245309 p.Val693Ile missense_variant 0.1
embB 4249516 c.3003G>T synonymous_variant 0.12