TB-Profiler result

Run: ERR9891978
Summary

Run ID: ERR9891978

Sample name:

Date: 02-04-2023 13:26:06

Number of reads: 1494184

Percentage reads mapped: 99.06

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6798 p.Gly520Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575578 c.231G>C synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rpsA 1834372 p.Lys277Asn missense_variant 0.11
tlyA 1917827 c.-113C>A upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101699 c.1344G>T synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3236c 3612360 p.Gly253Trp missense_variant 0.17
Rv3236c 3612778 p.Leu113Phe missense_variant 0.11
fbiB 3642405 p.His291Asn missense_variant 0.13
clpC1 4038936 p.Thr590Ile missense_variant 0.12
embC 4240801 c.939C>T synonymous_variant 0.15
embC 4240803 p.Tyr314Phe missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245539 c.-975C>G upstream_gene_variant 0.17
embB 4246544 p.Thr11Pro missense_variant 0.11
embB 4249732 c.3219C>G synonymous_variant 1.0
aftB 4267671 p.Ala389Glu missense_variant 0.14
aftB 4267992 p.Thr282Met missense_variant 1.0
aftB 4268803 p.Ala12Ser missense_variant 0.12
ubiA 4268947 p.Gly296Val missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0