TB-Profiler result

Run: SRR023446

Summary

Run ID: SRR023446

Sample name:

Date: 02-04-2023 14:11:36

Number of reads: 201792

Percentage reads mapped: 96.31

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7820 c.519G>A synonymous_variant 0.4
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765032 p.Ala555Ser missense_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800800 c.-9G>C upstream_gene_variant 0.4
Rv1258c 1407318 p.Pro8Leu missense_variant 0.67
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471878 n.33C>A non_coding_transcript_exon_variant 0.18
rrl 1474284 n.627G>T non_coding_transcript_exon_variant 0.15
PPE35 2168543 c.2070G>T synonymous_variant 0.12
PPE35 2168789 c.1824C>A synonymous_variant 0.15
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
pepQ 2860545 c.-127G>C upstream_gene_variant 0.4
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449644 p.Ala381Ser missense_variant 0.29
fbiA 3640379 c.-164T>C upstream_gene_variant 1.0
alr 3840225 p.Thr399Asn missense_variant 0.67