TB-Profiler result

Run: SRR034934

Summary

Run ID: SRR034934

Sample name:

Date: 02-04-2023 14:16:41

Number of reads: 33583032

Percentage reads mapped: 98.95

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762836 c.-534C>G upstream_gene_variant 0.34
mmpL5 777399 p.Thr361Arg missense_variant 0.17
fbiC 1303174 p.Leu82Val missense_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.17
PPE35 2169320 p.Leu431Phe missense_variant 0.23
PPE35 2169866 c.747G>C synonymous_variant 0.19
pepQ 2859381 c.1038C>G synonymous_variant 0.28
clpC1 4038857 c.1848C>A synonymous_variant 0.15
clpC1 4039932 p.Gly258Val missense_variant 0.2
panD 4043882 p.Pro134Ser missense_variant 1.0
embC 4242425 p.Arg855Gly missense_variant 0.2
embC 4242822 p.Val987Gly missense_variant 0.26
ubiA 4269529 p.Ala102Gly missense_variant 0.24