TB-Profiler result

Run: SRR10851615
Summary

Run ID: SRR10851615

Sample name:

Date: 02-04-2023 19:29:55

Number of reads: 1030717

Percentage reads mapped: 87.0

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.41
rpoB 760871 c.1065C>T synonymous_variant 0.14
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776795 c.1686C>T synonymous_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406363 c.978A>C synonymous_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474364 n.707G>T non_coding_transcript_exon_variant 0.2
rrl 1476183 n.2526A>C non_coding_transcript_exon_variant 0.22
rrl 1476330 n.2673A>C non_coding_transcript_exon_variant 0.17
inhA 1674703 c.502T>C synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169295 p.Gly440Arg missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859375 c.1044G>A synonymous_variant 0.14
Rv2752c 3065198 p.Asp332Tyr missense_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4241104 p.Glu414Asp missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246316 c.-198T>C upstream_gene_variant 0.1
embA 4246459 p.Glu1076Val missense_variant 0.14
embB 4249079 p.Ser856Gly missense_variant 0.11
embB 4249408 c.2895G>A synonymous_variant 1.0
ethA 4326620 p.His285Arg missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0