TB-Profiler result

Run: SRR10869255
Summary

Run ID: SRR10869255

Sample name:

Date: 02-04-2023 19:45:36

Number of reads: 3837560

Percentage reads mapped: 99.58

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761161 p.Leu452Pro missense_variant 0.99 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575761 c.414C>T synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.27
rpoB 759814 p.Asp3Gly missense_variant 1.0
rpoC 763407 p.Gly13Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781502 c.-58G>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99
pepQ 2860159 p.Ala87Gly missense_variant 0.16
fbiD 3339734 p.Ala206Gly missense_variant 0.31
fprA 3474361 c.355C>T synonymous_variant 1.0
alr 3840887 c.534G>A synonymous_variant 1.0
rpoA 3878637 c.-130G>C upstream_gene_variant 0.14
embB 4246584 p.Arg24Pro missense_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0