TB-Profiler result

Run: SRR1140740
Summary

Run ID: SRR1140740

Sample name:

Date: 2024-10-04T15:09:28.942276

Number of reads: 601681

Percentage reads mapped: 46.87

Median coverage: 9.0

Strain: lineage4.6.1.2

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6 Euro-American None 1.0
lineage4.6.1.2 Euro-American RD724 0.98
lineage4 Euro-American None 1.0
lineage4.6.1 Euro-American (Uganda) RD724 0.95
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6501 p.Arg421His missense_variant 1.0 levofloxacin
moxifloxacin
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.5 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R