TB-Profiler result

Run: SRR1173658
Summary

Run ID: SRR1173658

Sample name:

Date: 03-04-2023 03:29:27

Number of reads: 213722

Percentage reads mapped: 16.85

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5721 p.Gly161Val missense_variant 0.33
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8065 p.Gly255Glu missense_variant 0.67
gyrA 8387 c.1086C>T synonymous_variant 0.4
gyrA 8650 p.Arg450Leu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575223 c.-125G>T upstream_gene_variant 0.5
rpoC 764006 p.Gln213Lys missense_variant 1.0
rpoC 764207 p.Val280Ile missense_variant 0.5
rpoC 766876 p.Asp1169Glu missense_variant 0.5
embR 1417018 c.330C>T synonymous_variant 0.67
katG 2154135 c.1977G>A synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
Rv2752c 3064964 c.1227_1228insCC frameshift_variant 0.4
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiA 3641115 p.Glu191Asp missense_variant 0.67
alr 3841143 p.Thr93Ile missense_variant 1.0
alr 3841244 c.177G>A synonymous_variant 0.67
clpC1 4038185 c.2520G>T synonymous_variant 0.5
embC 4242075 p.Arg738Gln missense_variant 1.0
embC 4242097 c.2235C>A synonymous_variant 0.5
embA 4242769 c.-464C>A upstream_gene_variant 1.0
embB 4247609 p.Ser366Thr missense_variant 0.33
embB 4247853 p.Thr447Ile missense_variant 1.0