TB-Profiler result

Run: SRR11972310
Summary

Run ID: SRR11972310

Sample name:

Date: 03-04-2023 05:36:29

Number of reads: 20870

Percentage reads mapped: 77.55

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 620625 p.Ile245Met missense_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 1.0
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.5
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.5
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.5
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.67
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.67
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.25
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.25
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.25
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.25
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.33
rrl 1476513 n.2856G>A non_coding_transcript_exon_variant 0.33
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.33
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.33
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.33
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.33
rrl 1476544 n.2887T>C non_coding_transcript_exon_variant 0.33
rrl 1476545 n.2888C>T non_coding_transcript_exon_variant 0.33
katG 2154724 p.Arg463Leu missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474067 p.Ser21Pro missense_variant 0.67
embA 4242628 c.-605C>T upstream_gene_variant 0.5
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247792 c.1279C>A synonymous_variant 1.0
aftB 4268655 p.Thr61Lys missense_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0