TB-Profiler result

Run: SRR12199462
Summary

Run ID: SRR12199462

Sample name:

Date: 03-04-2023 06:41:54

Number of reads: 88666

Percentage reads mapped: 39.55

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 8543 c.1242C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 767093 p.Ser1242Gly missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781491 c.-69C>T upstream_gene_variant 1.0
fbiC 1303529 p.Glu200Gly missense_variant 0.5
Rv1258c 1406613 p.Glu243Ala missense_variant 1.0
embR 1416310 c.1038G>A synonymous_variant 0.17
embR 1417019 p.Cys110Tyr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473071 n.1226C>T non_coding_transcript_exon_variant 0.25
rrl 1476312 n.2655T>G non_coding_transcript_exon_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2169902 p.Leu237Phe missense_variant 0.4
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
eis 2714503 p.His277Pro missense_variant 0.33
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
folC 2746962 p.Ala213Thr missense_variant 1.0
Rv2752c 3064632 c.1560C>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568572 c.108C>T synonymous_variant 0.5
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4243336 p.Pro35Gln missense_variant 0.67
embA 4243848 p.Val206Met missense_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
ethR 4326739 c.-810G>A upstream_gene_variant 1.0
ethA 4326917 p.Thr186Met missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407756 c.447C>T synonymous_variant 0.67
gid 4407873 c.330G>T synonymous_variant 1.0