TB-Profiler result

Run: SRR13837452
Summary

Run ID: SRR13837452

Sample name:

Date: 03-04-2023 09:10:44

Number of reads: 881564

Percentage reads mapped: 97.02

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7837 p.Gly179Val missense_variant 1.0
rpoB 762257 c.2451C>G synonymous_variant 1.0
mmpL5 777730 p.Gly251Arg missense_variant 1.0
fbiC 1304816 p.His629Arg missense_variant 1.0
fbiC 1304869 p.Leu647Met missense_variant 1.0
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.13
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.12
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.16
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.14
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.12
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.12
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.13
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.13
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.11
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.11
tlyA 1918527 c.588G>T synonymous_variant 1.0
ndh 2102259 p.Ser262Ala missense_variant 1.0
ndh 2102557 c.485delG frameshift_variant 1.0
katG 2156260 c.-149C>A upstream_gene_variant 1.0
PPE35 2169123 p.Thr497Ile missense_variant 1.0
Rv2752c 3066145 p.Leu16Ser missense_variant 1.0
Rv3236c 3612326 p.Thr264Ile missense_variant 1.0
Rv3236c 3612504 p.His205Tyr missense_variant 1.0
Rv3236c 3612779 p.Leu113* stop_gained 1.0
fbiB 3640821 c.-714G>C upstream_gene_variant 1.0
rpoA 3878381 p.Leu43Met missense_variant 1.0
rpoA 3878543 c.-36G>C upstream_gene_variant 1.0
embC 4240536 c.678delC frameshift_variant 1.0
embB 4248562 c.2049G>C synonymous_variant 1.0