TB-Profiler result

Run: SRR13837543
Summary

Run ID: SRR13837543

Sample name:

Date: 03-04-2023 09:12:50

Number of reads: 588709

Percentage reads mapped: 97.19

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5540 p.Thr101Ser missense_variant 1.0
rpoB 760091 c.285G>C synonymous_variant 0.12
rpoB 760101 c.295T>C synonymous_variant 0.12
rpoB 760110 p.Ser102Thr missense_variant 0.12
rpoB 760118 c.312T>G synonymous_variant 0.12
rpoB 760121 c.315T>C synonymous_variant 0.12
rpoB 760130 p.Asp108Glu missense_variant 0.11
rpoB 760139 c.333A>G synonymous_variant 0.11
rpoB 760181 c.375T>C synonymous_variant 0.11
rpoB 760184 c.378A>G synonymous_variant 0.11
rpoB 760196 c.390C>G synonymous_variant 0.11
rpoB 760558 c.753delC frameshift_variant 1.0
rpoB 760611 p.Leu269Val missense_variant 1.0
rpoB 762490 p.Val895Gly missense_variant 1.0
rpoC 764560 c.1191T>C synonymous_variant 0.12
rpoC 764575 c.1206T>G synonymous_variant 0.13
rpoC 764611 c.1242G>T synonymous_variant 0.15
rpoC 764626 c.1257C>T synonymous_variant 0.15
rpoC 764758 c.1389C>G synonymous_variant 0.12
rpoC 764791 c.1422C>G synonymous_variant 0.15
rpoC 764803 c.1434C>T synonymous_variant 0.14
rpoC 764809 c.1440C>T synonymous_variant 0.13
rpoC 764810 p.Pro481Ala missense_variant 0.13
rpoC 764815 c.1446A>G synonymous_variant 0.13
rpoC 764824 c.1455T>C synonymous_variant 0.13
rpoC 764827 c.1458G>C synonymous_variant 0.12
rpoC 765707 c.2340delA frameshift_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.12
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.12
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.14
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.11
ndh 2101690 p.Glu451Asp missense_variant 1.0
PPE35 2168961 p.Gly551Val missense_variant 1.0
Rv1979c 2222084 p.Leu361Ile missense_variant 1.0
Rv1979c 2222431 p.Met245Arg missense_variant 0.96
ald 3087020 c.201C>T synonymous_variant 1.0
alr 3841157 c.264A>G synonymous_variant 1.0
rpoA 3878047 p.Ala154Asp missense_variant 1.0
rpoA 3878193 c.315T>C synonymous_variant 0.13
rpoA 3878196 p.Glu104Ala missense_variant 0.13
rpoA 3878205 c.303T>C synonymous_variant 0.12
rpoA 3878217 c.291A>G synonymous_variant 0.13
rpoA 3878259 c.249G>C synonymous_variant 0.12
rpoA 3878271 c.237T>C synonymous_variant 0.12
rpoA 3878283 p.Glu75Asp missense_variant 0.11
rpoA 3878292 c.216T>C synonymous_variant 0.12
rpoA 3878298 c.210A>G synonymous_variant 0.12
rpoA 3878301 c.207C>G synonymous_variant 0.11
rpoA 3878310 c.198G>T synonymous_variant 0.11
rpoA 3878313 c.195G>C synonymous_variant 0.11
rpoA 3878322 c.186A>G synonymous_variant 0.11
clpC1 4039070 c.1635G>C synonymous_variant 0.1
clpC1 4039078 p.Lys543Gln missense_variant 0.1
clpC1 4039121 c.1584T>C synonymous_variant 0.15
clpC1 4039142 c.1563A>G synonymous_variant 0.11
clpC1 4039145 c.1560G>C synonymous_variant 0.11
clpC1 4039178 c.1527G>C synonymous_variant 0.11
clpC1 4039183 c.1522T>C synonymous_variant 0.12
clpC1 4039190 c.1515C>T synonymous_variant 0.12
embB 4247452 c.939C>T synonymous_variant 1.0
ethR 4326799 c.-750G>A upstream_gene_variant 1.0