TB-Profiler result

Run: SRR13837568
Summary

Run ID: SRR13837568

Sample name:

Date: 03-04-2023 09:13:24

Number of reads: 587695

Percentage reads mapped: 96.02

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5785 c.546C>T synonymous_variant 1.0
gyrB 6314 c.1076dupC frameshift_variant 1.0
gyrA 7495 p.Arg65His missense_variant 1.0
gyrA 8780 p.Asp493Glu missense_variant 1.0
ccsA 620129 p.Gly80Ala missense_variant 1.0
rpoB 761845 p.Gln680Arg missense_variant 1.0
rplC 800937 c.129A>G synonymous_variant 1.0
embR 1416298 c.1050G>C synonymous_variant 1.0
rrl 1475592 n.1935A>T non_coding_transcript_exon_variant 1.0
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.22
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.27
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.26
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.23
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.23
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.23
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.18
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.19
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.19
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.19
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.19
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.13
tlyA 1918324 p.Val129Leu missense_variant 1.0
PPE35 2168503 p.Phe704Leu missense_variant 1.0
PPE35 2168604 p.Pro670His missense_variant 1.0
ahpC 2726771 c.579T>A synonymous_variant 1.0
folC 2746808 p.Ala264Gly missense_variant 1.0
Rv2752c 3067057 c.-867_-866insG upstream_gene_variant 1.0
ald 3087587 c.769delC frameshift_variant 1.0
fbiA 3641252 p.Thr237Ser missense_variant 1.0
rpoA 3877496 p.Glu338* stop_gained 1.0
ddn 3986684 c.-160G>C upstream_gene_variant 1.0
embC 4240480 c.618G>A synonymous_variant 1.0
embA 4244410 p.Trp393Ser missense_variant 1.0
embB 4249447 c.2934G>A synonymous_variant 1.0
whiB6 4338681 c.-160A>T upstream_gene_variant 1.0