TB-Profiler result

Run: SRR13837590
Summary

Run ID: SRR13837590

Sample name:

Date: 03-04-2023 09:13:55

Number of reads: 591326

Percentage reads mapped: 98.62

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9502 p.Arg734His missense_variant 1.0
rpoB 759681 c.-126C>T upstream_gene_variant 1.0
rpoB 761239 p.Cys478Tyr missense_variant 1.0
mmpL5 776185 p.Lys766Glu missense_variant 1.0
mmpL5 779400 c.-920C>A upstream_gene_variant 1.0
rrs 1472865 n.1020C>G non_coding_transcript_exon_variant 1.0
tlyA 1918063 p.Pro42Ala missense_variant 1.0
ndh 2102985 p.Ile20Val missense_variant 1.0
katG 2155856 p.Thr86Ser missense_variant 1.0
PPE35 2169233 c.1379delT frameshift_variant 1.0
Rv2752c 3065376 c.815delT frameshift_variant 1.0
Rv2752c 3066351 c.-160G>T upstream_gene_variant 1.0
thyX 3067731 p.Val72Ala missense_variant 0.92
thyX 3067825 p.Arg41Gly missense_variant 0.96
thyA 3074334 c.138T>C synonymous_variant 0.11
thyA 3074339 p.Leu45Ile missense_variant 0.11
thyA 3074360 c.112T>C synonymous_variant 0.11
thyA 3074361 c.111T>C synonymous_variant 0.11
fbiD 3338949 c.-169_-168insT upstream_gene_variant 1.0
Rv3083 3448707 c.204G>A synonymous_variant 1.0
Rv3083 3449768 p.Thr422Lys missense_variant 1.0
fbiB 3641403 c.-132C>T upstream_gene_variant 1.0
alr 3841257 p.His55Leu missense_variant 1.0
rpoA 3877601 p.Gln303* stop_gained 1.0
ddn 3986668 c.-176T>C upstream_gene_variant 1.0
embC 4241864 p.Leu668Met missense_variant 1.0
embB 4245557 c.-957G>A upstream_gene_variant 1.0
ethA 4327092 p.Ala128Pro missense_variant 1.0
gid 4408151 p.Leu18Val missense_variant 1.0