TB-Profiler result

Run: SRR13837602
Summary

Run ID: SRR13837602

Sample name:

Date: 2024-03-26T12:24:20.359521

Number of reads: 293844

Percentage reads mapped: 100.0

Median coverage: 10.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5709 p.Gly157Val missense_variant 1.0 levofloxacin
moxifloxacin
rpoB 762279 c.2474delA frameshift_variant 1.0 rifampicin
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
eis 2714940 c.392delA frameshift_variant 1.0 amikacin Uncertain significance
kanamycin Uncertain significance
ald 3087311 c.492C>G synonymous_variant 1.0 cycloserine
Rv3236c 3613629 c.-513C>G upstream_gene_variant 1.0 pyrazinamide
rpoA 3878288 p.Thr74Pro missense_variant 1.0 rifampicin
embA 4243235 c.3G>T synonymous_variant 1.0 ethambutol