TB-Profiler result

Run: SRR13837627

Summary

Run ID: SRR13837627

Sample name:

Date: 03-04-2023 09:14:40

Number of reads: 293937

Percentage reads mapped: 95.03

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5922 p.Glu228Gly missense_variant 1.0
gyrB 7242 p.Lys668Thr missense_variant 1.0
ccsA 620360 p.Tyr157Ser missense_variant 1.0
rpoB 761356 c.1550_1551insA frameshift_variant 1.0
rpoC 763347 c.-23C>G upstream_gene_variant 1.0
rpoC 766025 p.Val886Met missense_variant 1.0
mmpL5 776145 p.Ala779Gly missense_variant 1.0
mmpL5 776954 p.Lys509Asn missense_variant 1.0
rplC 801231 c.423C>A synonymous_variant 1.0
atpE 1460916 c.-129G>A upstream_gene_variant 1.0
rrl 1476201 n.2544C>G non_coding_transcript_exon_variant 1.0
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.18
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.4
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.36
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.42
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.42
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.5
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.46
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.47
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.47
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.47
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.44
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.46
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.33
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.22
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.2
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.2
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.2
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.2
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.2
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.2
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.2
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.2
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.2
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.2
katG 2155137 c.975G>C synonymous_variant 1.0
PPE35 2168892 p.Thr574Lys missense_variant 1.0
Rv1979c 2222852 p.Ala105Thr missense_variant 1.0
folC 2747046 p.Asn185Asp missense_variant 0.18
ribD 2987259 p.Leu141Val missense_variant 1.0
Rv2752c 3065161 p.Asn344Thr missense_variant 1.0
Rv2752c 3065830 p.Ile121Thr missense_variant 1.0
Rv2752c 3067100 c.-909G>A upstream_gene_variant 1.0
fbiD 3339117 c.-1C>T upstream_gene_variant 1.0
Rv3083 3448661 p.Val53Ala missense_variant 1.0
Rv3236c 3612041 p.Val359Glu missense_variant 1.0
fbiA 3640418 c.-125C>A upstream_gene_variant 1.0
rpoA 3877877 p.Ala211Ser missense_variant 1.0
clpC1 4039250 c.1455C>G synonymous_variant 1.0
embC 4242113 c.2251C>T synonymous_variant 1.0
embB 4246367 c.-147C>T upstream_gene_variant 1.0
whiB6 4338567 c.-46C>T upstream_gene_variant 1.0
gid 4408302 c.-101delC upstream_gene_variant 1.0