TB-Profiler result

Run: SRR13837646
Summary

Run ID: SRR13837646

Sample name:

Date: 03-04-2023 09:15:03

Number of reads: 294165

Percentage reads mapped: 98.12

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
fgd1 490955 p.Met58Arg missense_variant 1.0
rpoC 762962 c.-408C>T upstream_gene_variant 0.18
rpoC 763031 c.-339T>G upstream_gene_variant 0.14
rpoC 763034 c.-336C>G upstream_gene_variant 0.12
rpoC 763040 c.-330C>G upstream_gene_variant 0.12
rpoC 763070 c.-300T>C upstream_gene_variant 0.12
rpoC 763082 c.-288C>T upstream_gene_variant 0.12
rpoC 763094 c.-276G>C upstream_gene_variant 0.11
rpoC 764626 c.1257C>T synonymous_variant 0.15
rpoC 764632 c.1263T>C synonymous_variant 0.15
mmpS5 779639 c.-735dupG upstream_gene_variant 1.0
fbiC 1304529 c.1599T>C synonymous_variant 1.0
Rv1258c 1406845 p.Ala166Pro missense_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.13
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.14
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.17
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.17
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.17
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.18
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.15
inhA 1674607 p.Pro136Ser missense_variant 1.0
inhA 1674778 p.Pro193Ala missense_variant 1.0
PPE35 2169081 p.Leu511Ser missense_variant 1.0
PPE35 2169202 p.Ser471Pro missense_variant 1.0
Rv1979c 2222091 c.1074G>T synonymous_variant 1.0
Rv1979c 2223306 c.-142T>A upstream_gene_variant 1.0
pncA 2289228 p.Ile5Asn missense_variant 1.0
kasA 2518176 p.Ala21Gly missense_variant 1.0
eis 2714755 p.Pro193Gln missense_variant 1.0
ahpC 2726324 c.132A>G synonymous_variant 1.0
ahpC 2726362 p.Phe57Ser missense_variant 1.0
pepQ 2859580 p.Leu280Arg missense_variant 1.0
pepQ 2859999 c.420G>T synonymous_variant 1.0
thyX 3067940 c.6C>G synonymous_variant 1.0
thyA 3074620 c.-149C>A upstream_gene_variant 1.0
fprA 3473861 c.-146T>G upstream_gene_variant 1.0
fprA 3474953 p.Gln316Arg missense_variant 1.0
ddn 3986889 p.Phe16Val missense_variant 1.0
embC 4242041 p.Met727Leu missense_variant 1.0
embA 4244723 p.Gln497His missense_variant 1.0
aftB 4267979 c.858G>C synonymous_variant 1.0
ethA 4326503 p.Gly324Glu missense_variant 0.25