Run ID: SRR13837649
Sample name:
Date: 2024-10-04T19:30:49.043163
Number of reads: 293856
Percentage reads mapped: 95.02
Median coverage: 10.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 9490 | p.Gly730Asp | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13883 | c.-325T>A | upstream_gene_variant | 1.0 | isoniazid | |
fgd1 | 491231 | p.Phe150Tyr | missense_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rpsL | 781503 | c.-57T>C | upstream_gene_variant | 1.0 | streptomycin | |
rplC | 800381 | c.-428A>G | upstream_gene_variant | 1.0 | linezolid | Uncertain significance |
sigE | 1364655 | p.Met81Ile | missense_variant | 1.0 | pyrazinamide | |
Rv1258c | 1407463 | c.-123G>C | upstream_gene_variant | 1.0 | streptomycin | |
pyrazinamide | ||||||
isoniazid | ||||||
rrl | 1474235 | n.578G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475139 | n.1482C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476248 | n.2591G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476576 | n.2919C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
bacA | 2063299 | p.Trp477Leu | missense_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
folC | 2746788 | p.Ala271Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067214 | p.Ser244Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
fbiD | 3339396 | c.279C>T | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rpoA | 3878048 | p.Ala154Ser | missense_variant | 1.0 | rifampicin | |
panD | 4044922 | c.-641G>T | upstream_gene_variant | 1.0 | pyrazinamide | |
ethA | 4327097 | p.Leu126His | missense_variant | 1.0 | ethionamide | |
gid | 4407792 | c.411G>C | synonymous_variant | 1.0 | streptomycin |