TB-Profiler result

Run: SRR13837692
Summary

Run ID: SRR13837692

Sample name:

Date: 03-04-2023 09:16:01

Number of reads: 293889

Percentage reads mapped: 96.02

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9502 p.Arg734His missense_variant 1.0
rpoB 759681 c.-126C>T upstream_gene_variant 1.0
rpoB 761239 p.Cys478Tyr missense_variant 1.0
mmpL5 776185 p.Lys766Glu missense_variant 1.0
mmpL5 779400 c.-920C>A upstream_gene_variant 1.0
rrs 1472865 n.1020C>G non_coding_transcript_exon_variant 1.0
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.18
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.22
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.22
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.25
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.25
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.25
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.2
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.22
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.22
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.22
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.33
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.27
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.22
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.2
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.2
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.2
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.2
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.2
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.2
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.22
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.22
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.22
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.22
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.22
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.22
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.22
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.22
tlyA 1918063 p.Pro42Ala missense_variant 1.0
ndh 2102985 p.Ile20Val missense_variant 1.0
katG 2155856 p.Thr86Ser missense_variant 1.0
PPE35 2169233 c.1379delT frameshift_variant 1.0
Rv2752c 3065376 c.815delT frameshift_variant 1.0
Rv2752c 3066351 c.-160G>T upstream_gene_variant 1.0
thyX 3067731 p.Val72Ala missense_variant 1.0
thyX 3067825 p.Arg41Gly missense_variant 1.0
fbiD 3338949 c.-169_-168insT upstream_gene_variant 1.0
Rv3083 3448707 c.204G>A synonymous_variant 1.0
Rv3083 3449768 p.Thr422Lys missense_variant 1.0
fbiB 3641403 c.-132C>T upstream_gene_variant 1.0
alr 3841257 p.His55Leu missense_variant 1.0
rpoA 3877601 p.Gln303* stop_gained 1.0
ddn 3986668 c.-176T>C upstream_gene_variant 1.0
embC 4241864 p.Leu668Met missense_variant 1.0
embB 4245557 c.-957G>A upstream_gene_variant 1.0
ethA 4327092 p.Ala128Pro missense_variant 1.0
gid 4408151 p.Leu18Val missense_variant 1.0