TB-Profiler result

Run: SRR13837698
Summary

Run ID: SRR13837698

Sample name:

Date: 2024-04-15T17:19:40.190757

Number of reads: 293834

Percentage reads mapped: 97.0

Median coverage: 10.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rpoB 760454 c.650delG frameshift_variant 1.0 rifampicin
rpoC 765487 p.Met706Ile missense_variant 1.0 rifampicin
Rv1129c 1254452 p.Glu28Ala missense_variant 1.0 moxifloxacin
levofloxacin
rifampicin
isoniazid
rrs 1471874 n.29A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064843 c.-115C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
PPE35 2170198 p.Ala139Ser missense_variant 1.0 pyrazinamide
eis 2714922 c.411G>A synonymous_variant 1.0 amikacin
kanamycin
mtrB 3625436 p.Ile393Asn missense_variant 1.0 bedaquiline
rifampicin
alr 3840711 p.Ser237Leu missense_variant 1.0 cycloserine
embC 4242023 p.Val721Leu missense_variant 1.0 ethambutol