TB-Profiler result

Run: SRR13837759

Summary

Run ID: SRR13837759

Sample name:

Date: 03-04-2023 09:17:47

Number of reads: 147417

Percentage reads mapped: 95.32

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6624 p.Ser462* stop_gained 1.0
gyrA 7285 c.-17T>C upstream_gene_variant 1.0
gyrA 8798 c.1497C>T synonymous_variant 1.0
rpoC 764438 c.1069_1070insA frameshift_variant 1.0
mmpL5 775795 p.Ala896Ser missense_variant 1.0
mmpS5 778619 p.Ala96Val missense_variant 0.29
fbiC 1303593 c.663G>A synonymous_variant 1.0
embR 1416428 c.919_920insT frameshift_variant 1.0
rrs 1471798 n.-48G>A upstream_gene_variant 1.0
rrs 1472913 n.1068G>C non_coding_transcript_exon_variant 1.0
rrl 1476167 n.2510T>A non_coding_transcript_exon_variant 1.0
inhA 1674226 p.Arg9Trp missense_variant 1.0
rpsA 1833352 c.-190C>A upstream_gene_variant 1.0
rpsA 1833710 p.Tyr57Asp missense_variant 0.75
ndh 2102326 c.717G>T synonymous_variant 1.0
Rv1979c 2222739 c.426C>A synonymous_variant 1.0
Rv1979c 2222936 p.Ala77Thr missense_variant 1.0
eis 2714217 c.1115dupC frameshift_variant 1.0
eis 2714361 c.972C>A synonymous_variant 1.0
pepQ 2859813 p.Ile202Met missense_variant 1.0
pepQ 2860286 p.Val45Leu missense_variant 1.0
ribD 2987503 p.Gly222Val missense_variant 1.0
ald 3087394 p.Ala192Val missense_variant 1.0
embC 4241874 p.Leu671Arg missense_variant 1.0
embC 4242816 p.Trp985* stop_gained 1.0
embB 4248365 p.Val618Met missense_variant 1.0
aftB 4267893 p.Ile315Ser missense_variant 1.0
aftB 4268516 c.321A>G synonymous_variant 1.0
ethR 4326691 c.-858C>A upstream_gene_variant 1.0