TB-Profiler result

Run: SRR13837763
Summary

Run ID: SRR13837763

Sample name:

Date: 03-04-2023 09:17:53

Number of reads: 146914

Percentage reads mapped: 96.01

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6667 p.Gln476His missense_variant 1.0
gyrA 7289 c.-13_-12insT upstream_gene_variant 1.0
rpoB 760214 p.Asn136Lys missense_variant 1.0
fbiC 1304005 p.Pro359Ser missense_variant 1.0
rrs 1471943 n.98T>C non_coding_transcript_exon_variant 1.0
rrs 1472075 n.230A>C non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>T non_coding_transcript_exon_variant 1.0
rrs 1473370 n.1525T>C non_coding_transcript_exon_variant 1.0
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.33
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.5
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.5
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.33
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.67
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.5
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.4
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.6
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.75
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.4
fabG1 1673813 p.Arg125Leu missense_variant 1.0
inhA 1674784 p.Arg195Gly missense_variant 1.0
ndh 2101793 p.Trp417* stop_gained 1.0
PPE35 2169624 p.Gly330Asp missense_variant 1.0
ahpC 2726213 c.21C>T synonymous_variant 1.0
ribD 2987016 p.Gly60Arg missense_variant 1.0
Rv2752c 3065644 p.Thr183Ser missense_variant 1.0
thyA 3074595 c.-124C>A upstream_gene_variant 1.0
alr 3841581 c.-161T>A upstream_gene_variant 1.0
embC 4242810 p.Leu983Gln missense_variant 1.0
embB 4246553 p.Arg14Trp missense_variant 1.0
embB 4248920 p.Val803Met missense_variant 1.0
embB 4249551 p.Arg1013Leu missense_variant 1.0
ethA 4326296 p.Leu393Gln missense_variant 1.0