TB-Profiler result

Run: SRR13837775

Summary

Run ID: SRR13837775

Sample name:

Date: 03-04-2023 09:18:17

Number of reads: 2944609

Percentage reads mapped: 98.22

Strain: lineage4.9

Drug-resistance: HR-TB


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155058 p.Gln352* stop_gained 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760182 p.Pro126Ala missense_variant 1.0
rrs 1472286 n.441C>T non_coding_transcript_exon_variant 1.0
rrs 1472762 n.917C>A non_coding_transcript_exon_variant 0.98
rrs 1472840 n.997delG non_coding_transcript_exon_variant 0.99
rpsA 1834279 c.738C>T synonymous_variant 1.0
ndh 2102692 c.350_351insA frameshift_variant 1.0
katG 2155551 c.561G>T synonymous_variant 1.0
eis 2715425 c.-93G>C upstream_gene_variant 1.0
fprA 3473990 c.-17A>T upstream_gene_variant 0.99
fprA 3474095 c.91delG frameshift_variant 1.0
fprA 3474441 c.436delT frameshift_variant 1.0
alr 3840436 p.Leu329Val missense_variant 1.0
clpC1 4038224 c.2481G>C synonymous_variant 0.99
clpC1 4038878 c.1826_1827insG frameshift_variant 1.0
aftB 4268216 p.Trp207Cys missense_variant 0.99
aftB 4268782 p.Trp19Arg missense_variant 1.0
aftB 4269678 c.-842C>T upstream_gene_variant 1.0
ubiA 4269868 c.-35G>C upstream_gene_variant 1.0
ethR 4327906 p.Val120Leu missense_variant 1.0