TB-Profiler result

Run: SRR13837781
Summary

Run ID: SRR13837781

Sample name:

Date: 03-04-2023 09:18:19

Number of reads: 147245

Percentage reads mapped: 98.22

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 763816 c.447C>G synonymous_variant 0.25
rpsA 1833851 p.Lys104Gln missense_variant 1.0
Rv1979c 2223241 c.-77C>G upstream_gene_variant 1.0
pncA 2289811 c.-570C>T upstream_gene_variant 1.0
pncA 2289994 c.-753A>C upstream_gene_variant 1.0
kasA 2518109 c.-6G>A upstream_gene_variant 0.5
kasA 2518301 p.His63Asp missense_variant 1.0
pepQ 2859859 p.Ala187Glu missense_variant 1.0
Rv2752c 3064886 p.Ala436Pro missense_variant 1.0
Rv2752c 3065258 p.Met312Val missense_variant 1.0
Rv3083 3449104 p.Pro201Ala missense_variant 1.0
Rv3236c 3612337 c.779delG frameshift_variant 1.0
fbiB 3641723 c.189T>C synonymous_variant 1.0
rpoA 3877740 c.768G>T synonymous_variant 1.0
embC 4241005 c.1143G>T synonymous_variant 1.0
embC 4241081 c.1220delT frameshift_variant 1.0
embC 4242746 p.Pro962Ser missense_variant 1.0
embA 4243969 p.Val246Ala missense_variant 1.0