TB-Profiler result

Run: SRR13837790
Summary

Run ID: SRR13837790

Sample name:

Date: 03-04-2023 09:18:35

Number of reads: 146912

Percentage reads mapped: 99.0

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5258 p.Lys7* stop_gained 1.0
gyrB 7122 c.1883_1884insA frameshift_variant 1.0
mmpL5 776374 p.Arg703Cys missense_variant 1.0
mmpR5 779126 p.Cys46Phe missense_variant 1.0
rplC 801447 p.Lys213Asn missense_variant 1.0
fbiC 1303004 p.Ala25Glu missense_variant 1.0
fbiC 1303171 p.Arg81Trp missense_variant 1.0
fbiC 1303517 p.Met196Thr missense_variant 1.0
rpsA 1834640 p.Glu367* stop_gained 1.0
ndh 2103004 c.39T>G synonymous_variant 1.0
PPE35 2170453 p.Gly54Ser missense_variant 1.0
Rv1979c 2223326 c.-162C>T upstream_gene_variant 1.0
pncA 2288748 p.Ala165Asp missense_variant 1.0
kasA 2518474 p.Glu120Asp missense_variant 1.0
thyX 3067529 c.417C>G synonymous_variant 1.0
thyA 3073764 c.708T>C synonymous_variant 1.0
thyA 3073862 p.Gly204Ser missense_variant 1.0
thyA 3073963 p.Leu170Gln missense_variant 1.0
fbiD 3339357 c.240G>T synonymous_variant 1.0
Rv3083 3448352 c.-152G>C upstream_gene_variant 1.0
Rv3083 3449624 p.Lys374Met missense_variant 1.0
fbiB 3642227 p.Gln231His missense_variant 1.0
fbiB 3642581 c.1047A>C synonymous_variant 1.0
embA 4244641 p.Val470Gly missense_variant 1.0
embA 4245197 c.1965C>T synonymous_variant 1.0
embB 4246641 p.Ala43Glu missense_variant 1.0
embB 4247233 p.Asp240Glu missense_variant 1.0
embB 4248572 p.His687Asn missense_variant 0.33
ethA 4327035 p.Tyr147Asp missense_variant 1.0
ethR 4327923 p.Gln125His missense_variant 1.0