TB-Profiler result

Run: SRR13837796
Summary

Run ID: SRR13837796

Sample name:

Date: 03-04-2023 09:18:45

Number of reads: 148273

Percentage reads mapped: 97.9

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8078 c.777A>G synonymous_variant 0.15
gyrA 8090 c.789C>G synonymous_variant 0.17
gyrA 8096 c.795T>C synonymous_variant 0.18
gyrA 8099 c.798T>C synonymous_variant 0.18
gyrA 8111 c.810G>C synonymous_variant 0.18
gyrA 8156 c.855T>C synonymous_variant 0.2
gyrA 8168 c.867A>G synonymous_variant 0.22
gyrA 8174 c.873C>G synonymous_variant 0.22
gyrA 8198 c.897T>C synonymous_variant 0.25
gyrA 8204 c.903C>T synonymous_variant 0.25
gyrA 8207 c.906T>C synonymous_variant 0.25
fgd1 490955 p.Met58Arg missense_variant 1.0
rpoB 760730 c.924T>C synonymous_variant 0.22
rpoB 760751 c.945G>C synonymous_variant 0.22
rpoB 760757 c.951T>C synonymous_variant 0.22
rpoB 760759 p.Val318Ala missense_variant 0.22
rpoB 760763 c.957C>T synonymous_variant 0.22
rpoB 760769 c.963C>G synonymous_variant 0.22
rpoB 760775 c.969G>C synonymous_variant 0.22
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.22
rpoB 760793 c.987A>G synonymous_variant 0.22
rpoB 760805 c.999G>C synonymous_variant 0.25
rpoB 760817 c.1011A>G synonymous_variant 0.29
rpoB 760820 c.1014T>C synonymous_variant 0.29
rpoB 760826 c.1020C>G synonymous_variant 0.25
rpoB 760830 c.1024T>C synonymous_variant 0.22
rpoB 760845 p.Thr347Pro missense_variant 0.3
rpoB 760859 c.1053T>C synonymous_variant 0.22
rpoB 760869 p.Val355Ile missense_variant 0.3
rpoB 760886 c.1080A>G synonymous_variant 0.29
rpoB 760919 c.1113C>G synonymous_variant 0.25
rpoB 760925 c.1119T>C synonymous_variant 0.25
rpoB 760928 c.1122G>C synonymous_variant 0.25
rpoB 760934 c.1128C>T synonymous_variant 0.25
rpoB 760946 c.1140A>G synonymous_variant 0.29
rpoB 760970 c.1164G>C synonymous_variant 0.29
rpoB 760982 c.1176G>C synonymous_variant 0.33
rpoB 760985 c.1179G>C synonymous_variant 0.33
rpoB 760991 c.1185G>C synonymous_variant 0.33
rpoB 761648 c.1842T>C synonymous_variant 0.4
rpoB 761657 c.1851C>G synonymous_variant 0.4
rpoB 762254 c.2448T>C synonymous_variant 0.29
rpoB 762293 c.2487T>C synonymous_variant 0.29
rpoB 762317 c.2511A>G synonymous_variant 0.25
rpoB 762329 c.2523G>C synonymous_variant 0.29
rpoB 762338 c.2532T>C synonymous_variant 0.29
rpoB 762347 c.2541T>C synonymous_variant 0.29
rpoB 762362 p.Glu852Asp missense_variant 0.33
mmpS5 779639 c.-735dupG upstream_gene_variant 1.0
fbiC 1303659 c.729T>C synonymous_variant 0.29
fbiC 1304499 c.1569T>G synonymous_variant 0.25
fbiC 1304517 c.1587C>T synonymous_variant 0.29
fbiC 1304520 c.1590A>C synonymous_variant 0.33
fbiC 1304523 c.1593G>T synonymous_variant 0.33
fbiC 1304526 c.1596T>G synonymous_variant 0.33
fbiC 1304529 c.1599T>C synonymous_variant 0.6
fbiC 1304544 c.1614T>C synonymous_variant 0.33
fbiC 1304545 p.Val539Thr missense_variant 0.33
fbiC 1304559 p.Glu543Asp missense_variant 0.29
fbiC 1304565 c.1635C>G synonymous_variant 0.29
fbiC 1304568 c.1638T>C synonymous_variant 0.29
fbiC 1304574 c.1644C>G synonymous_variant 0.25
fbiC 1304580 c.1650T>C synonymous_variant 0.25
fbiC 1304628 c.1698G>C synonymous_variant 0.25
Rv1258c 1406845 p.Ala166Pro missense_variant 1.0
inhA 1674607 p.Pro136Ser missense_variant 1.0
inhA 1674778 p.Pro193Ala missense_variant 1.0
PPE35 2169081 p.Leu511Ser missense_variant 1.0
PPE35 2169202 p.Ser471Pro missense_variant 1.0
Rv1979c 2222091 c.1074G>T synonymous_variant 1.0
Rv1979c 2223306 c.-142T>A upstream_gene_variant 1.0
kasA 2518176 p.Ala21Gly missense_variant 1.0
eis 2714755 p.Pro193Gln missense_variant 1.0
ahpC 2726324 c.132A>G synonymous_variant 1.0
ahpC 2726362 p.Phe57Ser missense_variant 1.0
pepQ 2859999 c.420G>T synonymous_variant 1.0
thyA 3074620 c.-149C>A upstream_gene_variant 1.0
fprA 3473861 c.-146T>G upstream_gene_variant 1.0
fprA 3474953 p.Gln316Arg missense_variant 1.0
embC 4240656 p.Ala265Gly missense_variant 0.4
embC 4242041 p.Met727Leu missense_variant 1.0
embA 4244723 p.Gln497His missense_variant 1.0
embB 4249369 c.2856T>C synonymous_variant 0.33
aftB 4267979 c.858G>C synonymous_variant 1.0