TB-Profiler result

Run: SRR13837809

Summary

Run ID: SRR13837809

Sample name:

Date: 03-04-2023 09:19:03

Number of reads: 147190

Percentage reads mapped: 97.18

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 759613 c.-194C>A upstream_gene_variant 1.0
rpoB 759854 p.Ser16Arg missense_variant 1.0
rpoC 765119 p.Gly584Arg missense_variant 1.0
rpoC 766845 p.Arg1159His missense_variant 1.0
mmpL5 776280 p.Arg734His missense_variant 1.0
mmpR5 778208 c.-782C>G upstream_gene_variant 1.0
fbiC 1305195 c.2265T>G synonymous_variant 1.0
Rv1258c 1406120 c.1221C>T synonymous_variant 1.0
embR 1417526 c.-180delA upstream_gene_variant 1.0
rrl 1473960 n.303T>G non_coding_transcript_exon_variant 1.0
rrl 1474016 n.359C>G non_coding_transcript_exon_variant 0.5
rpsA 1833623 c.82_83insG frameshift_variant 1.0
tlyA 1918515 c.576C>T synonymous_variant 1.0
katG 2155055 p.Tyr353Asn missense_variant 1.0
PPE35 2169626 c.987C>T synonymous_variant 1.0
eis 2714776 p.Val186Glu missense_variant 1.0
ahpC 2726084 c.-109C>A upstream_gene_variant 1.0
Rv2752c 3065052 p.Glu380Asp missense_variant 1.0
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0
thyA 3073902 c.570C>G synonymous_variant 1.0
clpC1 4040603 c.102T>G synonymous_variant 0.18
panD 4044175 p.Ala36Asp missense_variant 1.0
embC 4240583 p.Thr241Ala missense_variant 1.0
gid 4407696 c.507C>T synonymous_variant 1.0