TB-Profiler result

Run: SRR13837850

Summary

Run ID: SRR13837850

Sample name:

Date: 2024-04-15T10:14:38.678587

Number of reads: 146892

Percentage reads mapped: 99.0

Median coverage: 5.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
ald 3086631 c.-189A>G upstream_gene_variant 1.0 cycloserine
alr 3840284 p.Trp379* stop_gained 1.0 cycloserine
embB 4247839 c.1326G>A synonymous_variant 1.0 ethambutol
embB 4249763 p.Thr1084Pro missense_variant 1.0 ethambutol Uncertain significance