TB-Profiler result

Run: SRR13837860
Summary

Run ID: SRR13837860

Sample name:

Date: 03-04-2023 09:20:19

Number of reads: 148557

Percentage reads mapped: 97.07

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6403 c.-899T>C upstream_gene_variant 0.4
gyrA 6415 c.-887G>C upstream_gene_variant 0.4
rpoC 762698 c.-672C>T upstream_gene_variant 1.0
rpoB 762958 p.Leu1051Pro missense_variant 1.0
rpoC 765700 c.2331T>C synonymous_variant 0.25
rpoC 766345 c.2976T>C synonymous_variant 0.67
rpoC 766348 c.2979A>G synonymous_variant 0.67
rpoC 766357 c.2988C>T synonymous_variant 0.67
rpoC 766363 c.2994G>C synonymous_variant 0.67
rpoC 766366 c.2997C>G synonymous_variant 0.67
rpoC 766381 c.3012C>T synonymous_variant 0.67
rpoC 766384 c.3015A>G synonymous_variant 0.67
rpoC 766390 c.3021C>T synonymous_variant 0.67
rpoC 766393 c.3024C>G synonymous_variant 0.67
rpoC 766408 c.3039C>G synonymous_variant 0.67
rpoC 766411 c.3042C>G synonymous_variant 0.67
rpoC 766426 c.3057C>T synonymous_variant 0.67
rpoC 766447 c.3078T>C synonymous_variant 1.0
rpoC 766462 c.3093G>C synonymous_variant 0.5
rpoC 766522 c.3153C>G synonymous_variant 0.5
rpoC 766528 c.3159T>C synonymous_variant 0.5
rpoC 766531 c.3162G>C synonymous_variant 0.5
rpoC 766540 p.Asp1057Glu missense_variant 0.5
rpoC 766549 c.3180G>C synonymous_variant 0.5
rpoC 766573 c.3204T>C synonymous_variant 0.5
rpoC 766582 c.3213C>G synonymous_variant 0.5
rpoC 766583 p.Gly1072Ser missense_variant 0.5
rpoC 766591 c.3222A>G synonymous_variant 0.5
rpoC 766594 c.3225G>C synonymous_variant 0.5
rpoC 766597 c.3228C>G synonymous_variant 0.5
rpoC 766607 p.Ile1080Leu missense_variant 0.5
rpoC 766630 c.3261G>C synonymous_variant 0.5
fbiC 1302962 p.Ala11Gly missense_variant 1.0
fbiC 1303706 p.Leu259Arg missense_variant 1.0
fbiC 1305384 c.2454G>T synonymous_variant 1.0
Rv1258c 1406724 p.Gln206Leu missense_variant 1.0
embR 1416800 p.Ala183Gly missense_variant 1.0
fabG1 1673153 c.-287C>G upstream_gene_variant 1.0
rpsA 1833555 p.Thr5Ser missense_variant 1.0
rpsA 1834073 p.Lys178* stop_gained 1.0
PPE35 2167669 p.Phe982Leu missense_variant 1.0
Rv2752c 3066234 c.-43G>A upstream_gene_variant 1.0
fbiB 3642276 c.743delC frameshift_variant 1.0
rpoA 3878111 p.Lys133Gln missense_variant 1.0
embC 4240175 p.Leu105Met missense_variant 0.25
embC 4240654 c.792C>G synonymous_variant 0.29
embC 4240660 c.798C>G synonymous_variant 0.29
embA 4242703 c.-530C>T upstream_gene_variant 1.0
embB 4249144 c.2631G>C synonymous_variant 1.0