TB-Profiler result

Run: SRR13837863
Summary

Run ID: SRR13837863

Sample name:

Date: 03-04-2023 09:20:38

Number of reads: 2951663

Percentage reads mapped: 96.44

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2288784 p.Thr153Asn missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9494 p.Tyr731* stop_gained 1.0
fgd1 491771 p.Pro330Leu missense_variant 1.0
rpoB 762948 p.Gln1048Glu missense_variant 0.99
rpoC 767026 c.3657G>C synonymous_variant 0.97
fbiC 1303155 c.225G>C synonymous_variant 0.99
fbiC 1304225 p.Gly432Asp missense_variant 0.99
fbiC 1305046 p.Ser706Pro missense_variant 1.0
Rv1258c 1406433 c.907delA frameshift_variant 1.0
embR 1416546 p.Thr268Ser missense_variant 1.0
rrl 1474652 n.995T>G non_coding_transcript_exon_variant 0.96
ndh 2102315 p.Ile243Thr missense_variant 1.0
kasA 2518563 p.Ala150Gly missense_variant 0.98
kasA 2519015 p.Ser301Ala missense_variant 1.0
Rv3236c 3612913 p.Leu68Phe missense_variant 1.0
ethA 4326245 p.Asp410Ala missense_variant 1.0
ethR 4327132 c.-417G>A upstream_gene_variant 1.0
ethA 4327893 c.-420C>A upstream_gene_variant 1.0
gid 4408070 p.Trp45Arg missense_variant 1.0