TB-Profiler result

Run: SRR13837953
Summary

Run ID: SRR13837953

Sample name:

Date: 03-04-2023 09:22:50

Number of reads: 1469046

Percentage reads mapped: 98.0

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6715 c.-587C>T upstream_gene_variant 1.0
mshA 575693 p.Pro116Ala missense_variant 1.0
rpoB 759863 p.Gln19His missense_variant 1.0
rpoB 760399 p.Val198Ala missense_variant 1.0
rpoB 763150 p.Phe1115Tyr missense_variant 1.0
rpoC 764516 p.Asp383Asn missense_variant 1.0
rpoC 766103 p.Arg912Gly missense_variant 1.0
mmpL5 777066 p.Ile472Ser missense_variant 1.0
ndh 2103185 c.-143A>C upstream_gene_variant 1.0
PPE35 2168894 c.1718dupG frameshift_variant 1.0
PPE35 2170039 p.Ala192Thr missense_variant 1.0
Rv1979c 2221777 p.Ala463Val missense_variant 1.0
kasA 2518793 p.Ser227Thr missense_variant 1.0
ahpC 2726300 c.108C>A synonymous_variant 1.0
folC 2747094 p.Asp169His missense_variant 1.0
Rv2752c 3064936 p.Ser419* stop_gained 1.0
Rv2752c 3065523 c.669C>T synonymous_variant 1.0
Rv2752c 3066039 c.153C>T synonymous_variant 1.0
alr 3841286 c.135T>A synonymous_variant 1.0
clpC1 4039368 p.Lys446Thr missense_variant 1.0
embC 4241777 p.Gly639Ser missense_variant 1.0
ubiA 4269888 c.-55C>A upstream_gene_variant 1.0