TB-Profiler result

Run: SRR13837966
Summary

Run ID: SRR13837966

Sample name:

Date: 03-04-2023 09:23:08

Number of reads: 1469062

Percentage reads mapped: 100.0

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8880 p.Lys527Gln missense_variant 1.0
rpoB 760972 p.Arg389Leu missense_variant 1.0
rpoC 765111 p.Met581Lys missense_variant 1.0
rpoC 765161 p.Glu598Lys missense_variant 1.0
rpoC 765540 p.Ala724Val missense_variant 1.0
rpoC 767068 c.3699G>T synonymous_variant 1.0
mmpR5 778439 c.-551C>A upstream_gene_variant 1.0
rplC 801357 p.His183Gln missense_variant 1.0
fbiC 1304229 c.1301delC frameshift_variant 1.0
rrs 1472288 n.444delT non_coding_transcript_exon_variant 1.0
tlyA 1917989 p.Ala17Gly missense_variant 1.0
ndh 2102525 p.Phe173Tyr missense_variant 1.0
ndh 2102538 c.504_505insT frameshift_variant 1.0
Rv1979c 2222978 p.Ile63Phe missense_variant 1.0
Rv1979c 2223052 p.Glu38Val missense_variant 1.0
pncA 2289415 c.-174C>G upstream_gene_variant 1.0
kasA 2518057 c.-58A>C upstream_gene_variant 1.0
kasA 2518799 p.Pro229Ser missense_variant 1.0
eis 2714983 p.Ala117Glu missense_variant 1.0
fbiA 3640404 c.-139C>A upstream_gene_variant 1.0
fbiB 3642056 c.522C>G synonymous_variant 1.0
rpoA 3877967 p.Thr181Ser missense_variant 1.0
rpoA 3877972 c.535delG frameshift_variant 1.0
clpC1 4039777 c.927_928insG frameshift_variant 1.0
embB 4247545 p.Ser344Arg missense_variant 0.98
aftB 4268812 p.Ser9Pro missense_variant 1.0