TB-Profiler result

Run: SRR13861181
Summary

Run ID: SRR13861181

Sample name:

Date: 03-04-2023 09:25:24

Number of reads: 84159

Percentage reads mapped: 1.68

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760591 p.Val262Ala missense_variant 0.29
rpoB 760611 c.805T>C synonymous_variant 0.29
rpoB 760634 c.828T>C synonymous_variant 0.33
rpoB 760646 c.840C>G synonymous_variant 0.33
rpoB 760655 c.849A>G synonymous_variant 0.33
rpoB 760661 c.855A>C synonymous_variant 0.33
rpoB 760670 c.864G>C synonymous_variant 0.33
rpoB 760674 c.868T>C synonymous_variant 0.33
rpoB 760679 c.873A>G synonymous_variant 0.33
rpoB 760683 c.877T>C synonymous_variant 0.33
rpoB 761847 p.Cys681Ser missense_variant 0.5
rpoB 762958 p.Leu1051Pro missense_variant 1.0
rpoC 765577 c.2208G>T synonymous_variant 0.67
rpoC 767233 c.3864T>C synonymous_variant 0.5
fbiC 1302962 p.Ala11Gly missense_variant 1.0
fbiC 1303706 p.Leu259Arg missense_variant 1.0
fbiC 1305384 c.2454G>T synonymous_variant 1.0
Rv1258c 1406724 p.Gln206Leu missense_variant 1.0
rrs 1472176 n.331G>T non_coding_transcript_exon_variant 0.67
rpsA 1833555 p.Thr5Ser missense_variant 1.0
rpsA 1834073 p.Lys178* stop_gained 1.0
Rv2752c 3066234 c.-43G>A upstream_gene_variant 1.0
fbiB 3642276 c.743delC frameshift_variant 1.0
rpoA 3877638 c.870T>C synonymous_variant 0.29
rpoA 3878111 p.Lys133Gln missense_variant 1.0
clpC1 4039430 c.1275T>C synonymous_variant 0.67
clpC1 4039442 c.1263A>G synonymous_variant 0.5
embB 4247876 c.1363C>T synonymous_variant 0.5
embB 4247881 c.1368G>C synonymous_variant 0.5
embB 4247887 c.1374C>T synonymous_variant 0.5
embB 4247890 c.1377C>T synonymous_variant 0.5
embB 4247899 p.Met462Ile missense_variant 0.5
embB 4249144 c.2631G>C synonymous_variant 1.0