TB-Profiler result

Run: SRR13861435

Summary

Run ID: SRR13861435

Sample name:

Date: 2024-10-04T00:30:35.086709

Number of reads: 193642

Percentage reads mapped: 3.23

Median coverage: 6.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rpoB 760399 p.Val198Ala missense_variant 1.0 rifampicin
mmpL5 777066 p.Ile472Ser missense_variant 1.0 bedaquiline
clofazimine
kasA 2518793 p.Ser227Thr missense_variant 1.0 isoniazid
lpqB 3623677 p.Val412Phe missense_variant 1.0 rifampicin
bedaquiline