TB-Profiler result

Run: SRR13861455
Summary

Run ID: SRR13861455

Sample name:

Date: 2024-10-05T14:21:22.102747

Number of reads: 190796

Percentage reads mapped: 3.18

Median coverage: 6.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5258 p.Lys7* stop_gained 1.0 levofloxacin Uncertain significance
moxifloxacin
fbiC 1303004 p.Ala25Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303517 p.Met196Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642227 p.Gln231His missense_variant 1.0 pretomanid
delamanid
clofazimine
embA 4244641 p.Val470Gly missense_variant 1.0 ethambutol
embA 4245197 c.1965C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ethA 4327035 p.Tyr147Asp missense_variant 1.0 ethionamide