TB-Profiler result

Run: SRR13861628
Summary

Run ID: SRR13861628

Sample name:

Date: 2024-04-16T05:50:08.714527

Number of reads: 249119

Percentage reads mapped: 4.99

Median coverage: 8.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mmpS5 778811 p.Phe32Ser missense_variant 1.0 clofazimine
bedaquiline
rrl 1475224 n.1567T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
bacA 2063516 p.Val405Ile missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
Rv1979c 2221853 p.Phe438Ile missense_variant 1.0 clofazimine
bedaquiline
embC 4240425 p.Arg188Pro missense_variant 1.0 ethambutol
embA 4244849 c.1617C>G synonymous_variant 1.0 ethambutol