TB-Profiler result

Run: SRR14781930
Summary

Run ID: SRR14781930

Sample name:

Date: 03-04-2023 11:05:49

Number of reads: 5229525

Percentage reads mapped: 99.51

Strain: lineage4.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.98
gyrA 8619 c.1318T>C synonymous_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
rpoB 759613 c.-194C>T upstream_gene_variant 0.96
rpoC 765150 p.Gly594Glu missense_variant 0.99
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168863 c.1750C>T synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.14
pepQ 2860159 p.Ala87Gly missense_variant 0.16
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.46
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.24
rpoA 3878082 c.426T>C synonymous_variant 0.99
rpoA 3878637 c.-130G>C upstream_gene_variant 0.18
rpoA 3878641 c.-134C>G upstream_gene_variant 0.46
embC 4240409 p.Pro183Ala missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.99
embB 4246436 c.-78G>A upstream_gene_variant 0.99
embB 4246527 p.Ala5Gly missense_variant 0.22
embB 4246584 p.Arg24Pro missense_variant 0.19
embB 4248324 p.Ala604Gly missense_variant 0.19
embB 4249408 c.2895G>A synonymous_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408040 p.Ile55Val missense_variant 0.99