TB-Profiler result

Run: SRR15368714
Summary

Run ID: SRR15368714

Sample name:

Date: 03-04-2023 13:44:34

Number of reads: 4913902

Percentage reads mapped: 65.86

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 0.99
ccsA 620329 p.Ile147Val missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156031 p.Lys27Asn missense_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474350 p.Pro115Leu missense_variant 1.0
fprA 3474760 c.754C>T synonymous_variant 0.99
Rv3236c 3612071 p.Pro349Leu missense_variant 0.99
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
ddn 3986663 c.-181G>A upstream_gene_variant 0.99
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267954 p.Ala295Thr missense_variant 0.99
whiB6 4338242 p.Gln94* stop_gained 0.23
whiB6 4338247 p.Leu92Ser missense_variant 0.11
whiB6 4338296 p.Trp76Gly missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0