TB-Profiler result

Run: SRR16134493
Summary

Run ID: SRR16134493

Sample name:

Date: 03-04-2023 16:27:18

Number of reads: 2222887

Percentage reads mapped: 34.15

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 0.2 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7504 p.Arg68Pro missense_variant 0.29
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760868 c.1062C>T synonymous_variant 1.0
rpoB 761202 p.Val466Leu missense_variant 1.0
mmpL5 779116 c.-636G>A upstream_gene_variant 0.2
mmpL5 779307 c.-827T>C upstream_gene_variant 0.3
mmpL5 779319 c.-839T>C upstream_gene_variant 0.33