TB-Profiler result

Run: SRR16134495
Summary

Run ID: SRR16134495

Sample name:

Date: 03-04-2023 16:27:19

Number of reads: 3094806

Percentage reads mapped: 70.79

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 1.0 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7499 c.198G>C synonymous_variant 0.33
gyrA 7501 p.Asp67Gly missense_variant 0.4
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760855 p.Thr350Ser missense_variant 1.0
rpoB 760860 p.Pro352Ala missense_variant 0.93
rpoB 760868 c.1062C>T synonymous_variant 1.0
rpoB 761202 p.Val466Leu missense_variant 0.99
fabG1 1673561 p.Lys41Thr missense_variant 0.75