TB-Profiler result

Run: SRR16134505
Summary

Run ID: SRR16134505

Sample name:

Date: 03-04-2023 16:27:54

Number of reads: 5447850

Percentage reads mapped: 62.73

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7495 p.Arg65Pro missense_variant 0.28
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760858 p.Val351Asp missense_variant 0.5
rpoB 760860 p.Pro352Ala missense_variant 0.9
rpoB 760868 c.1062C>T synonymous_variant 1.0
rpoB 761202 p.Val466Leu missense_variant 0.99
mmpL5 778932 c.-452A>G upstream_gene_variant 1.0
mmpL5 779116 c.-636G>A upstream_gene_variant 0.26
mmpL5 779307 c.-827T>C upstream_gene_variant 0.59
mmpL5 779319 c.-839T>C upstream_gene_variant 0.46
mmpR5 779329 p.Leu114Val missense_variant 1.0
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0
fabG1 1673271 c.-169G>C upstream_gene_variant 1.0