TB-Profiler result

Run: SRR16134510
Summary

Run ID: SRR16134510

Sample name:

Date: 03-04-2023 16:28:14

Number of reads: 6882566

Percentage reads mapped: 65.08

Strain: lineage4.9

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 0.98 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7510 p.His70Pro missense_variant 0.4
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 761011 p.Asp402Val missense_variant 1.0
rpoB 761125 p.Leu440Arg missense_variant 0.26
rpoB 761202 p.Val466Leu missense_variant 0.96
mmpL5 778932 c.-452A>G upstream_gene_variant 1.0
mmpL5 779307 c.-827T>C upstream_gene_variant 0.31
mmpL5 779319 c.-839T>C upstream_gene_variant 0.28
mmpR5 779329 p.Leu114Val missense_variant 1.0
fabG1 1673271 c.-169G>C upstream_gene_variant 1.0