TB-Profiler result

Run: SRR18715050

Summary

Run ID: SRR18715050

Sample name:

Date: 03-04-2023 20:16:32

Number of reads: 2798472

Percentage reads mapped: 99.24

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6054 p.His272Pro missense_variant 0.99
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417211 p.Arg46His missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154980 c.1132C>T synonymous_variant 0.99
PPE35 2168460 p.Asn718Ser missense_variant 1.0
PPE35 2170811 c.-199C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.13
fbiD 3339734 p.Ala206Gly missense_variant 0.73
fbiD 3339746 p.Ala210Gly missense_variant 0.29
fbiD 3339749 p.Val211Ala missense_variant 0.14
fprA 3474031 p.Val9Met missense_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.3
rpoA 3878597 c.-90G>C upstream_gene_variant 0.22
rpoA 3878641 c.-134C>G upstream_gene_variant 0.82
embC 4240409 p.Pro183Ala missense_variant 0.26
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.18
embB 4246529 p.Ser6Arg missense_variant 0.2
embB 4246584 p.Arg24Pro missense_variant 0.3
embB 4248328 c.1815G>C synonymous_variant 0.26
embB 4249522 c.3009C>T synonymous_variant 1.0
aftB 4268076 p.Met254Ala missense_variant 1.0
whiB6 4338538 c.-17T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0