TB-Profiler result

Run: SRR18715116
Summary

Run ID: SRR18715116

Sample name:

Date: 03-04-2023 20:19:46

Number of reads: 3117282

Percentage reads mapped: 99.55

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6358 c.-944C>T upstream_gene_variant 0.98
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.22
mshA 576618 p.His424Pro missense_variant 0.16
rpoC 764367 p.Gly333Ala missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.25
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305060 c.2130C>T synonymous_variant 0.98
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.26
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.45
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.22
pepQ 2860159 p.Ala87Gly missense_variant 0.13
fbiD 3339734 p.Ala206Gly missense_variant 0.5
whiB7 3568428 c.252A>G synonymous_variant 0.18
rpoA 3878597 c.-90G>C upstream_gene_variant 0.56
rpoA 3878641 c.-134C>G upstream_gene_variant 0.57
embC 4240409 p.Pro183Ala missense_variant 0.25
embC 4240768 c.906G>A synonymous_variant 0.96
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.4
embB 4248328 c.1815G>C synonymous_variant 0.16
embB 4249732 c.3219C>G synonymous_variant 0.95
whiB6 4338595 c.-75delG upstream_gene_variant 1.0