TB-Profiler result

Run: SRR18715219

Summary

Run ID: SRR18715219

Sample name:

Date: 03-04-2023 20:24:38

Number of reads: 4822452

Percentage reads mapped: 99.5

Strain: lineage4.1

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.25
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747160 p.Pro147Ser missense_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.68
fbiD 3339736 p.Thr207Pro missense_variant 0.33
fbiD 3339739 p.Ala208Pro missense_variant 0.33
fbiD 3339751 p.Ala212Pro missense_variant 0.27
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.29
whiB7 3568431 c.249C>G synonymous_variant 0.25
rpoA 3878641 c.-134C>G upstream_gene_variant 0.5
panD 4044304 c.-23C>G upstream_gene_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 0.99
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.29
embB 4248328 c.1815G>C synonymous_variant 0.21
embB 4249408 c.2895G>A synonymous_variant 1.0
ubiA 4269295 p.Met180Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408004 p.Asp67His missense_variant 0.98