TB-Profiler result

Run: SRR18715394
Summary

Run ID: SRR18715394

Sample name:

Date: 03-04-2023 20:32:19

Number of reads: 2739302

Percentage reads mapped: 99.65

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6988 c.-314C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491693 p.Gly304Asp missense_variant 1.0
mshA 576456 p.Val370Gly missense_variant 0.42
ccsA 620619 c.729G>A synonymous_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.28
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.3
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102817 p.Leu76Val missense_variant 0.16
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289302 c.-61C>T upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.27
pepQ 2860159 p.Ala87Gly missense_variant 0.12
fbiD 3339734 p.Ala206Gly missense_variant 0.5
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474077 p.Lys24Thr missense_variant 0.19
whiB7 3568428 c.252A>G synonymous_variant 0.33
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.3
rpoA 3878641 c.-134C>G upstream_gene_variant 0.62
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245835 p.Leu868Arg missense_variant 0.21
embB 4246527 p.Ala5Gly missense_variant 0.3
embB 4246544 p.Thr11Pro missense_variant 0.12
embB 4246555 c.42G>C synonymous_variant 0.12
embB 4246556 p.Ala15Pro missense_variant 0.12
embB 4247016 p.Ser168Trp missense_variant 0.45
embB 4247020 c.507C>G synonymous_variant 0.25
embB 4247033 p.Ser174Arg missense_variant 0.24
embB 4248328 c.1815G>C synonymous_variant 0.21
ethA 4327310 p.Ser55Cys missense_variant 1.0
ethA 4327412 p.Trp21Ser missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0