TB-Profiler result

Run: SRR18912067
Summary

Run ID: SRR18912067

Sample name:

Date: 03-04-2023 20:48:16

Number of reads: 106908

Percentage reads mapped: 99.66

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6127 c.888G>T synonymous_variant 0.25
gyrA 6328 c.-974C>T upstream_gene_variant 0.5
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7555 p.His85Arg missense_variant 0.67
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8983 p.Cys561Phe missense_variant 0.29
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9687 p.Arg796Trp missense_variant 0.22
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 619950 c.60G>A synonymous_variant 0.4
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761318 c.1512G>T synonymous_variant 0.25
rpoB 762405 p.Val867Leu missense_variant 0.33
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 764718 p.Glu450Gly missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781629 p.Leu24Val missense_variant 0.67
rplC 800635 c.-174G>A upstream_gene_variant 0.67
fbiC 1303016 p.Val29Gly missense_variant 0.36
fbiC 1305075 p.Ser715Arg missense_variant 0.29
fbiC 1305443 p.Glu838Val missense_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472002 n.157A>G non_coding_transcript_exon_variant 0.33
rrs 1473260 n.1415G>A non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102734 c.309G>A synonymous_variant 0.25
katG 2154155 p.Leu653Met missense_variant 0.12
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156429 c.-318C>T upstream_gene_variant 0.29
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289878 c.-637C>T upstream_gene_variant 0.4
kasA 2518917 p.Ala268Val missense_variant 0.4
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ribD 2987187 c.349C>T synonymous_variant 1.0
Rv2752c 3065159 p.Glu345* stop_gained 0.67
Rv2752c 3065694 c.498G>A synonymous_variant 0.33
thyX 3067592 c.354G>T synonymous_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641755 p.Arg74His missense_variant 0.33
alr 3841204 p.Gly73Ser missense_variant 0.29
alr 3841299 p.Asp41Gly missense_variant 0.2
clpC1 4038660 c.2044delT frameshift_variant 0.14
clpC1 4040207 c.498T>C synonymous_variant 0.4
panD 4043995 p.Ala96Asp missense_variant 0.4
embC 4239788 c.-75C>T upstream_gene_variant 0.33
embC 4239883 c.25delC frameshift_variant 0.18
embC 4239907 c.45A>C synonymous_variant 0.15
embC 4240862 p.Trp334Arg missense_variant 0.4
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246921 c.408G>C synonymous_variant 1.0
embB 4249399 c.2886G>T synonymous_variant 1.0
ethA 4326152 p.Arg441His missense_variant 0.29
ethA 4326291 p.Ala395Thr missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407880 p.Leu108Gln missense_variant 0.25
gid 4407980 p.Pro75Ser missense_variant 1.0