TB-Profiler result

Run: SRR19303804

Summary

Run ID: SRR19303804

Sample name:

Date: 03-04-2023 21:07:28

Number of reads: 3599577

Percentage reads mapped: 99.73

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7825 p.Ala175Gly missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472819 n.974T>A non_coding_transcript_exon_variant 0.22
fabG1 1673553 p.Asp38Glu missense_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746926 p.Asp225Asn missense_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.23
fbiD 3339734 p.Ala206Gly missense_variant 0.85
fbiD 3339746 p.Ala210Gly missense_variant 0.25
rpoA 3877554 c.954G>A synonymous_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243081 c.-152T>G upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.43
embB 4248328 c.1815G>C synonymous_variant 0.16
whiB6 4338595 c.-75delG upstream_gene_variant 1.0