TB-Profiler result

Run: SRR19976649

Summary

Run ID: SRR19976649

Sample name:

Date: 03-04-2023 21:47:37

Number of reads: 1049434

Percentage reads mapped: 99.87

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mmpR5 779387 c.400dupC frameshift_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.17
Rv1258c 1407148 p.Ala65Ser missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2169823 p.Ala264Thr missense_variant 0.12
fbiD 3339671 p.Leu185Gln missense_variant 0.14
fprA 3474952 p.Gln316Lys missense_variant 0.12
fprA 3475303 p.Ala433Ser missense_variant 0.11
fbiB 3641820 p.Glu96Lys missense_variant 0.12
fbiB 3642421 p.Arg296Leu missense_variant 0.12
embC 4242371 p.Ala837Thr missense_variant 0.22
embC 4242381 p.Pro840His missense_variant 0.18